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Statements


OTUB1 activates PI3K. 3 / 3
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"Recently, positive regulators of OTUB1 have been identified, for example, OTUB1 promotes immunosuppression of various cancer cells via targeting PD-L1, and regulates the transcription and post-transcr[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"OTUB1 contributed to HCC progression by activating PI3K/AKT and FAK/ERK signaling in a RACK1-dependent manner."

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"Therefore, OTUB1 significantly increased multiple oncogenes expression and activated PI3K/AKT and FAK/ERK signaling in a RACK1-dependent manner in HCC."