IndraLab

Statements

sparser
"When comparing the amount of drug remaining on the skin surface after 8 h from the different formulations; 69.76 ± 4.83%, 55.29 ± 4.04%, 44.15 ± 5.50% and 48.86 ± 2.37%, for the CAM-Sol, CAM-Lip, CS-C[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
28506801
sparser
"The bioadhesion of the different hydrogel formulations (CS-hydrogel, CS-CAM and CS-CAM-Lip) to the pig skin was tested using a TA."
28506801
sparser
"However, the CS-CAM-Lip only enhanced the penetration of CAM as compared to the CAM-Lip formulation (two-tailed t -test, p < 0.05), and showed a higher retention of CAM on the skin surface than the CS[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
28506801
sparser
"The bioadhesive properties of the final liposome-in-hydrogel formulation (CS-CAM-Lip) were compared with the plain CS-hydrogel and hydrogel containing unentrapped CAM (CS-CAM)."
28506801
sparser
"It appears that all the test formulations (CAM-Lip, CS-CAM, CS-CAM-Lip), although acting as the penetration enhancers for CAM, also serve to increase the drug concentration in the skin."
28506801
sparser
"The results in Fig. 1 also indicate decreased skin permeation of CAM from liposome dispersion (CAM-Lip), compared to the hydrogel formulation with unentrapped CAM (CS-CAM) after 8 h."
28506801
sparser
"Drug release from different vehicles (CS-CAM, CS-CAM-Lip and CAM-Lip) and further permeation through the pig skin, were investigated using Franz diffusion cells (PermeGear, Bethlehem, USA) with a 5 ml[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
28506801
sparser
"This might be explained by the absence of a liposomal carrier in the CS-CAM formulation, as the liposomes are expected to retain the drug in the skin and improve drug deposition."
28506801
sparser
"The total drug recovery was found to be good and of the same magnitude for all the formulations; 95.37 ± 4.61%, 93.84 ± 3.27%, 96.52 ± 5.71 and 94.26 ± 5.39%, for the CAM-Sol, CAM-Lip, CS-CAM and CS-C[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
28506801