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CALM1 activates ADCY. 7 / 7
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"As a result, there is the possibility of a negative feedback loop: calcium-calmodulin can immediately activate CAMKK, whereas CAM-dependent adenylate cyclase activation could trigger cAMP to activate [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"The observed constitutive GPCR phosphorylation of a CAM beta 2 receptor causes blunting of the subsequent adenylate cyclase activation, leading to an underestimation of the actual GPCR activity [32]."
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"Activation of brain adenylate cyclase by calmo dulin."
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"However, cal- modulin activates adenylate cyclase in only a few tissues (3-6) suggesting a specific site of action associated with some but not all cyclases."
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"10 Gnegy, M.E., Murihead, N. and Harrison, J.K., Regulation of cal- modulin- and dopamine stimulated adenylate cyclase activities by light in bovine retina, J. Neurochem., 42 (1984) 1632-1640."
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"Gnegy M. E., Murihead N. and Harrison J. K. (1984) Regulation of calmodulin- and dopamine- stimulated adenylate cyclase activities by light in bovine retina."
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"These results suggest that the Ca2 +-dependent binding of cal- modulin to specific high affinity sites on brain membranes regulates the activation of adenylate cyclase by cal- modulin."
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