IndraLab

Statements

USP36 binds YAP1. 7 / 7
| 1 6
sparser
"USP36 interacts with YAP and inhibits YAP polyubiquitination and breakdown, which further promotes esophageal cancer progression (Fig. xref )."
36470870
sparser
"USP36 could associate with YAP and deubiquitinate YAP protein, which further leads to enhanced Hippo/YAP activity."
36470870
sparser
"Molecular studies demonstrated that USP36 associated with the YAP protein and enhanced YAP protein stability by blocking the K48-linked polyubiquitination of YAP."
36470870
sparser
"USP36 could interact with the YAP protein and inhibit YAP K48-linked polyubiquitination."
36470870
reach
"USP36 could associate with YAP and deubiquitinate YAP protein, which further leads to enhanced Hippo/YAP activity."
36470870
sparser
"These findings indicate that USP36 interacts with YAP and plays a role in deubiquitinating YAP, thereby positively influencing Hippo/YAP signaling activity."
38785979
sparser
"We made deletion constructs targeting these domains for interaction analysis, which revealed that the WW domain was necessary for the binding of YAP to USP36, while the USP domain was required for the association of USP36 with YAP (Fig. xref )."
36470870