IndraLab

Statements


LMP1 activates TNFAIP3. 3 / 3
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eidos
"A20 is induced by LMP1 via NF-KappaB as a negative feedback mechanism to block further activation of both canonical and non-canonical NF-KappaB , and JNK activation [ 21 , 138 ] ."

sparser
"A second possibility is A20, which is activated by both LMP1 ( Laherty et al. 1992 ) and CD40 ( Sarma et al. 1995 )."

eidos
"As described in a previous section , A20 induction by EBV LMP1 was shown to inhibit IRF7 , which consequently prevents IRF7dependent IFN induction ( Ning and Pagano , 2010 ) ."