IndraLab

Statements

reach
"In addition, USP13 disruption significantly reduced GSC proliferation (XREF_FIG) but showed little effects on NSTCs and NPCs (not depicted)."
27923907
reach
"In lung and ovarian cancers, where USP13 also regulates Mcl-1 stability, USP13 does not contribute to the cell proliferation of unstressed cells."
33627786
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"Further studies will be required to identify these targets and understand how they contribute to USP13 mediated cell proliferation."
33627786
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"XREF_FIG, USP13 deficiency significantly increased fibroblast proliferation."
26453058
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"Functionally, USP13 depletion led to decreased cell proliferation measured by two-dimensional (2D) colony formation and three-dimensional (3D) anchorage-independent growth."
36037364
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"Interestingly, despite the fact that the viral oncogenes do not regulate USP13 expression, depletion of USP13 in HPV- C33A cells did not cause a proliferation defect."
33627786
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"Furthermore, re-expression of cyclin D1 partially reversed the cell cycle arrest and cell proliferation inhibition induced by USP13 depletion in GC cells."
37311811
reach
"Two independent USP13 shRNAs (XREF_FIG) both markedly increased the proliferation (XREF_FIG) and anchorage independent growth (XREF_FIG) of SUM159 breast cancer cells, while restoration of PTEN (XREF_FIG) or expression of an RNAi resistant USP13 mutant (XREF_SUPPLEMENTARY) completely reversed the effect of USP13 shRNA (XREF_FIG)."
24270891
reach
"CK2-Mediated Phosphorylation Upregulates the Stability of USP13 and Promotes Ovarian Cancer Cell Proliferation."
36612196
reach
"Stable knockdown (KD) of USP13 by lentiviral short hairpin RNAs (shRNAs) markedly inhibited the proliferation of the USP13 amplified cell lines (CAOV3 and HeyA8) and the USP13 overexpressing cell line (OVCAR8)."
27892457
reach
"Next, USP13 knockdown prominently reduced the proliferation, epithelial-mesenchymal transition (EMT), migration, and invasion of Hep3B and Huh7 cells, while USP13 overexpression enhanced these biological behaviors of HepG2 and LO2 cells."
33195243