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OTUB1 activates Dendritic Cells. 2 / 2

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"In contrast, impaired OTUB1-deficient DC activation and cytokine production by OTUB1-deficient DCs protected mice from lipopolysaccharide-induced immunopathology."

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"As OTUB1 was described to modulate DC and T cell functions [10–13] we hypothesized that its loss may provoke perturbances in maternal immune responses and thereby interfere with fetal tolerance induction."

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Statements

OTUB1 activates Dendritic Cells. 2 / 2

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