IndraLab

Statements



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"USP18 reduced basal inflammation, senescence and insulin resistance in coronary endothelial cells."

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"From the transcriptomic analysis we selected USP18, previously shown to decrease inflammation and insulin-resistance."

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"USP18 silencing enhanced basal inflammation and senescence."

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"A partial form of inherited human USP18 deficiency underlies infection and inflammation."

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"The upregulation of USP18 ameliorated hind limbs ' motor function , inhibiting inflammation and apoptosis after SCII in rats ."

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"Our findings indicate that USP18 inhibition induces inflammation by increasing the STAT signaling and exacerbates IFN induced beta cell apoptosis by the mitochondrial pathway of cell death."