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USP46 deubiquitinates AR. 2 / 2

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"Furthermore, overexpressed USP46 was able to deubiquitinate AR, similarly to our previous observations for USP12 [XREF_BIBR]."

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"Here we report that the novel small molecule anti-androgen, galeterone targets USP12 and USP46, two highly homologous deubiquitinating enzymes that control the AR-AKT-MDM2-P53 signalling pathway."

29861848

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USP46 deubiquitinates AR. 2 / 2

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