IndraLab

Statements

MINDY1 activates YAP protein. 4 / 4
| 4
eidos
"Depletion of MINDY1 decreased the YAP protein level and the expression of YAP / TEAD target genes in bladder cancer , including CTGF , ANKRD1 and CYR61 ."
34315490
eidos
"We then depleted MINDY1 with two non-overlapping siRNAs separately in T24 and UMUC3 cells to further validate the function of MINDY1 in regulating YAP , as shown in Fig. 1B , C , MINDY1 depletion significantly decreased the YAP protein levels without influence on the expression of YAP mRNA ."
34315490
eidos
"A In the presence of the proteasome inhibitor MG132 , depletion of MINDY1 did not further decrease the YAP protein level ."
34315490
eidos
"Depletion of MINDY1 significantly decreased the YAP protein level and inhibited the Hippo signaling activity ."
34315490