IndraLab

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USP13 deubiquitinates MCL1. 6 / 6
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ubibrowser
"Collectively, we nominate USP13 as a novel deubiquitinase which regulates MCL1 turnover in diverse solid tumors and propose that USP13 may be a potential therapeutic target for the treatment of various malignancies."
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"Two DUBs USP9X and USP13 deubiquitinate and stabilise MCL1, and hypomorphic mutations in both have been linked to neurodevelopmental disorders and neurodegenerative disease [XREF_BIBR, XREF_BIBR]."
33414510
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"Next, we confirmed that USP13 deubiquitinated Mcl-1."
33627786
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"Therefore, USP13 interacted with and deubiquitinated MCL1 to preserve its protein stability."
29335437
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"USP13 interacts with and deubiquitinates Mcl-1 in cervical cancer cells."
33627786
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"USP13 interacts with and deubiquitinates MCL1."
29335437