IndraLab

Statements


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"However, it remains to be determined whether Sitagliptin inhibited NLRP3 inflammasome relying on the activation of NRF2.In addition, we also investigated the effects of Sitagliptin on gut microbiota after radiation."

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"Recently, it has been demonstrated that sitagliptin and linagliptin can suppress the activity of NLRP3/inflammasome in an experimental model of renal injury [141]."

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"Recently, it has been demonstrated that sitagliptin and linagliptin can suppress the activity of NLRP3 and inflammasome in an experimental model of renal injury [136]."

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"Animal studies have provided evidence that sitagliptin and linagliptin exhibit the ability to attenuate the activity of NLRP3/inflammasome (198)."

eidos
"Recently , it has been demonstrated that sitagliptin and linagliptin can suppress the activity of NLRP3 / inflammasome in an experimental model of renal injury [ 141 ] ."

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"18 Interestingly, some studies found that sitagliptin also inhibited the NLRP3 inflammasome 23 via an identical mechanism to that used by irisin to inhibit inflammatory cytokines."

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"Sitagliptin and linagliptin also suppressed the activity of NLRP3 and inflammasome in an experimental model of nephropathy."

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"Therefore, Sitagliptin was able to attenuate radiation-induced activation of NLRP3 inflammasome in intestinal epithelial cells."