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USP15 inhibits IRF3. 2 / 2

| 2

reach

"In addition, USP15 dose-dependently inhibited RIG-I-N-triggered IFN-beta-Luc, ISRE-Luc, NF-kappaB-Luc, and IRF3-Luc reporter activities."

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reach

"As shown in XREF_FIG e and XREF_FIG f, knockdown of USP15 increased the activation of NF-kappaB (5.9 vs 12.9, p = 1.92E-04) and IRF3 (15.6 vs 26.5, p = 1.04E-03) through reporter assays."

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IndraLab

Statements

USP15 inhibits IRF3. 2 / 2

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