IndraLab

Statements



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"USP14 and UCHL5 inhibitors induce accumulation of ubiquitinated proteins and endoplasmic reticulum stress response in ER + BCa."

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"Notably, in resting cells, USP14 tonically blocks ER associated degradation by interaction with IRE1alpha."

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"Inhibition of USP14 induces ER stress mediated autophagy without apoptosis in lung cancer cell line A549."

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"Inhibition of USP14 and UCHL5 activates caspase and triggers apoptosis of ER + BCa cells."