IndraLab

Statements

ATR phosphorylates USP28. 7 / 7
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sparser
"In response to DNA damage, phosphorylation of the deubiquitinase USP28 by DDR kinases, ATM, and ATR leads to deubiquitination of either GATA4 or its associated factor [ xref ]."
33557090
reach
"In response to DNA damage, phosphorylation of the deubiquitinase USP28 by DDR kinases, ATM, and ATR leads to deubiquitination of either GATA4 or its associated factor [XREF_BIBR]."
33557090
sparser
"The latest research has found that ATR phosphorylates USP28 (S67 and S714) and increases its enzymatic activity, further confirming that targeting the USP28-Np63 axis in sensitizing squamous cell tones down this DNA damage response pathways [ xref ]."
37450415
reach
"ATR phosphorylates USP28 and increases its enzymatic activity."
34611298
reach
"USP28 is also phosphorylated by ATR and ATM and is involved in the response to DNA damage by virtue of its ability to deubiquitinate and stabilize FBW7 (see below), the ubiquitin ligase involved in the degradation of the myc transcription factor."
19489724
sparser
"ATR phosphorylates USP28 and increases its enzymatic activity."
34611298
sparser
"We next asked whether ATM or ATR phosphorylates USP28 upon CPPD treatment."
34611298