IndraLab

Statements

BAP1 inhibits HDAC. 3 / 3
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reach
"Interestingly, HDAC4 is the only HDAC that is significantly upregulated by the loss of BAP1 in human uveal melanoma cells."
35430294
reach
"Since SAHA inhibits numerous HDACs, we questioned whether there may be a specific HDAC that is up-regulated by Bap1 loss and mediates the Bap1-deficient phenotype."
31555735
eidos
"Loss of BAP1 increases histone deacetylase levels , and a pre-clinical drug screen identified that pan-histone deacetylase inhibitors ( HDACi ) , such as quisinostat , are effective at inhibiting UM growth ( Kuznetsoff et al ., 2021 ) ."
35513054