IndraLab

Statements

CALM1 binds KIF1Bbeta. 5 / 5
| 5
reach
"Therefore, we asked if KIF1Bbeta binding to CALM2 is necessary for CN to dephosporylate DRP1.We first tested if the KIF1Bbeta600-1400 proapoptotic domain also co-precipitated with the CN catalytic sub[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
26812016
reach
"The association between KIF1Bbeta and CALM2 was confirmed in 1p36 positive neuroblastoma cells (SH-SY5Y) by co-immunoprecipitation of endogenous KIF1Bbeta with endogenous CALM2."
26812016
reach
"KIF1Bbeta mutants that failed to bind CALM2 but bind to CNA (1200-1600 and 600-1400del1100-1300) showed very weak binding to the p-DRP1 peptide and failed to activate CNA, indicating that direct inter[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
26812016
reach
"The direct binding of KIF1Bbeta to CALM2 or CNA does not require Ca 2+."
26812016
reach
"Although KIF1Bbeta can directly associate with CALM2 and CNA in the absence of Ca 2+, CNA substrate binding to P-DRP1 is Ca 2+ dependent, since Ca 2+ is required for the CALM2-CNA interaction as previ[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
26812016