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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

FASN activates USP14. 2 / 2

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"Co-expression of Flag tagged wild-type (WT) USP14, but not catalytically inactive (CI) USP14 31 or GFP, significantly increased the FASN half-life, further supporting the notion that USP14 could stabilize FASN protein."

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"Forth, our results demonstrated that FASN could be a direct target of USP14 to exert its function in hepatic DNL."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...