IndraLab

Statements


KCNQ2 binds apoCaM. 2 / 2
| 2

reach
"Importantly, coexpression of CaM1234 modestly reduced but did not abolish enrichment of HA-KCNQ3 and KCNQ2 channels at the axonal surface (XREF_FIG), suggesting that KCNQ2 binding to apoCaM but not Ca 2+ -bound CaM is required for targeting the channels to the axonal surface."

reach
"We interpret this as an indication that apoCaM binds the intact C-termini of KCNQ2 and KCNQ3 channels, and promotes their multimerization."