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ATXN3 bound to FOXO4 increases the amount of SOD2. 1 / 1

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"It is notable that Atxn3 interacts with mammalian FOXO4 and activates basal and stress induced expression of SOD2; this is opposite in C. elegans where Atxn3 KO exhibits enhanced transcription of sod-3 through DAF-16."

22777893

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IndraLab

Statements

ATXN3 bound to FOXO4 increases the amount of SOD2. 1 / 1

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