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USP8 activates STAT3. 3 / 3

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"Suppressing USP8 in ARID1A-deficient OCCC cells attenuates the STAT3 signaling."

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"Thus, the knockdown of USP8 significantly reduced the downstream targets of RTKs including STAT3, Akt, and ERKs both as a phosphorylated and unphosphorylated form in gefitinib-resistant and -sensitive[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In addition, inhibition of USP8 suppressed the STAT3 pathway, specifically in ARID1A-deficient cells."

40074856

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USP8 activates STAT3. 3 / 3

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