IndraLab

Statements

COPS5 decreases the amount of STAT3. 3 / 3
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"Moreover, the overexpression of COPS5 increased p-STAT3 level, while PVT1 knockdown or TRIM24 knockout caused a dramatic decrease in COPS5 overexpression-increased p-STAT3 level (Figure 8G)."
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"Furthermore, Jab1/CSN5 knockdown regulates signal transducer and activator of transcription 3 (STAT3) DNA-binding activity and increases STAT3 expression via protein-protein interaction in colon cancer cells ."
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"Moreover, JAB1 knockdown tended to increase the STAT3 expression levels in nuclear and cytoplasmic extracts."
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