IndraLab

Statements

Calcium(2+) inhibits TLR7. 3 / 3
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"However, in a later study, we have found that imiquimod also induces intracellular Ca 2+ signaling and action potentials in TLR7-deficient mouse sensory neurons [7] ."
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"However, we found that imiquimod triggers Ca 2+ signaling in TLR7-deficient DRG sensory neurons [7] ."
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"In addition, calcium depletion via EDTA in combination with the calcium ionophore A23187 also reduced cleavage of TLR7 and selectively impaired the response of THP-TLR7 to R837 but not to LPS."
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