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USP20 activates SQSTM1. 2 / 2

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"In their study, they found that USP20 increased the stability of p62 by deubiquitinating lysine 48 (K48)-linked polyubiquitination, promoting cell survival."

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"This study was conducted in a cervical cancer model and uncovered that USP20-mediated p62 stabilization and subsequent upregulation of p65/p50 activity contribute to cancer cell survival (24)."

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USP20 activates SQSTM1. 2 / 2

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