IndraLab

Statements


USP13 activates TCRalpha. 2 / 2
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"Immunoblotting confirmed that USP13 depletion caused more TCRalpha to partition into the NP40-insoluble fractions (XREF_FIG) compared to control cells."

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"When the degradation of the model ERAD substrate TCRalpha was examined in cells overexpressing either USP13 or the USP13 variants, we found that wild-type USP13 significantly increased the half-life of TCRalpha (from 1.6 hr to 4.6 hr)."