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OTUB1 inhibits ESR1. 2 / 2

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"OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity.|We show that OTUB1 negatively regulates transcription mediated by ERalpha in transient reporter gene assays and transcription mediated by endogenous ERalpha in Ishikawa endometrial cancer cells."

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"4.2.1.3 OTUB1 inhibits estrogen receptor alpha (ERalpha) function in endometrial cancer."

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IndraLab

Statements

OTUB1 inhibits ESR1. 2 / 2

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