IndraLab

Statements


SIRT6 inhibits USP10. 2 / 2
| 2

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"Limonin mediates the ubiquitination and degradation of SIRT6 by activating USP10, providing an attractive therapeutic target for cardiac hypertrophy."

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"Indeed, knockdown of SIRT6 in p53 +/+ cells partially reversed the suppressive activity of USP10."