IndraLab

Statements

sparser
"TQ inhibits TBK1 and lowers IFN expression by downregulating IRF-3."
34445781
sparser
"In addition, based on our findings, the role of TBK1 inhibition by TQ with respect to the endoplasmic reticulum (ER) signaling pathway could be addressed in the future studies."
29751576
sparser
"Therefore, it would be very interesting to explore the correlation of TBK1 inhibition by TQ and ER stress-mediated apoptosis which might be contributing to the anticancer activity of TQ."
29751576
reach
"Therefore, it would be very interesting to explore the correlation of TBK1 inhibition by TQ and ER stress mediated apoptosis which might be contributing to the anticancer activity of TQ."
29751576
sparser
"In another study, TQ inhibited TANK-binding kinase 1 (TBK1), lowered the type I interferons (IFN) mRNA expression and downregulated the interferon regulatory factor 3 (IRF-3) signaling pathways in lipopolysaccharides (LPS)-stimulated murine macrophage-like RAW264.7 cells [54]."
34445781