IndraLab

Statements


USP25 activates RIPK1. 2 / 2
| 2

reach
"However, we show AF6 promotes necroptosis via regulating the ubiquitination of RIPK1 by directly interact with the intermediate domain of RIPK1, which was mediated by the deubiquitylase enzyme USP21."

reach
"USP21 was reported to target RIPK1 and inhibit NF-kappaB activity 96, however mice lacking USP21 show no defect in NF-kappaB signalling 93."