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USP8 inhibits TRAF6. 2 / 2

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"Given that USP8 negatively regulates the TRAF6-associated signaling for the activation of NF-κB and autophagy, in the present study, we investigated the role of USP8 in liver cancer progression and tumorigenicity."

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"A knockdown of USP8 increases the K48-Ub of TRAF6 in both, HBL1 and HT ( Fig. 5 D)."

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IndraLab

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USP8 inhibits TRAF6. 2 / 2

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