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Nicorandil inhibits SCN5A. 2 / 2

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"Perfusion with nicorandil (20 μM) significantly reduced the CDI in Scn5a +/Δ hearts in both the epicardium, to 12.0 ± 2.5 ms, and endocardium, to −7.6 ± 1.4 ms (epicardium P < 0.01, endocardium P < 0.[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

19351517

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"Thus treatment with nicorandil reduced local critical intervals in both the epicardium and endocardium of Scn5a + /Δ hearts, in parallel with its antiarrhythmic effects."

19351517

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Nicorandil inhibits SCN5A. 2 / 2

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