IndraLab

Statements

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"Consistent with in vitro findings, downregulation of USP22 in ATC cells impeded tumor growth and lung metastasis in vivo."
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"Moreover, USP22 overexpression can promote EMT and TGF-beta expression, whereas depletion of USP22 can reverse EMT and reduce metastasis of lung adenocarcinomas."
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"XREF_BIBR Downregulation of USP22 has been shown to suppress osteosarcoma growth and metastasis through PI3K and Akt pathway."
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"Downregulation of USP22 Inhibited OS Tumor Growth and Metastasis In Vivo."
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"In addition, downregulation of USP22 suppressed OS tumor growth and metastasis in vivo."
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"Similarly, Zhao et al. reported that USP22 depletion suppressed cell survival and proliferation as well as tumor growth and lung metastasis of anaplastic thyroid carcinoma cells XREF_BIBR."
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"As expected, downregulation of USP22 suppressed OS tumor growth and metastasis in vivo."
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"We also showed that ablation of tumor cell-intrinsic USP22 suppressed metastasis of pancreatic tumor cells in a T cell dependent manner."
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"These results suggest that USP22 downregulation inhibited OS tumor growth and metastasis in vivo."
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"Collectively, these results suggested that USP22 depletion attenuates tumor growth and metastasis of ATC."
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