IndraLab

Statements



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"As expected , HAUSP indeed decreased Yap ubiquitination level , whereas HAUSP-CA exerted an opposite effect ( Fig. 6n ) ."

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"Thus , USP7 regulates NLRP3 inflammasome activation , and chemical inhibition of USP7 by P22077 promotes the ubiquitination level of NLRP3 and blocks inflammasome activation ( Palaz o n-Riquelme et al ., 2018 ) , indicating the multiple roles of USP7 ."

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"As described above for PTEN , this ubiquitination is reversed by USP7 ( 143 ) ."

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"USP7 combines with tumor necrosis factor receptor-associated factor 6 ( TRAF6 ) and inhibits its ubiquitination by impairing the Lys63-linked polyubiquitin chain ."