IndraLab

Statements


USP35 deubiquitinates BRPF1. 4 / 4
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"USP35 interacts with and deubiquitinates BRPF1 in PRAD cells."

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"USP35 deubiquitinates BRPF1 to activate SREBP2 expressions, thereby strengthening the MVA crosstalk in PRAD progression."

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"In addition, USP35 can accelerate prostate cancer growth by deubiquitinating BRPF1 [37]."

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"Mechanistically, we found that USP35 could directly deubiquitinate and stabilize BRPF1 proteins."