IndraLab

Statements


JSH-23 inhibits IFNB1. 1 / 1
| 1

reach
"To explore whether NF-kappaB is essential for HSV-1-induced early phase IFN-beta production, we pretreated BMMs with different doses of JSH-23, a specific inhibitor of NF-kappaB nuclear translocation and transcriptional activity, 12 before BMMs were subjected to HSV-1 infection for 4 h. ELISA revealed that JSH-23 potently inhibited HSV-1-induced early phase IFN-beta production at the dose as low as 2.5 muM and the inhibitory effect became more significant when the dose increased (XREF_FIG)."