IndraLab

Statements

USP22 activates Sirt1/JAK/STAT3. 5 / 5
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"In NSCLC, miR-30e-5p suppressed tumorigenesis and metastasis by inhibiting USP22-mediated Sirt1/JAK/STAT3 signaling."
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"26 Xu et al suggested that miR-30e-5p suppresses NSCLC tumorigenesis by targeting ubiquitin carboxyl-terminal hydrolase 22 mediated Sirt1/JAK/STAT3 signaling."
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"Taken together, our findings suggest that miR-30e-5p reduces NSCLC tumorigenesis by targeting USP22-mediated Sirt1/JAK/STAT3 signaling."
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"miR-30e-5p, a member of the miR-30 family, regulates the Sirt1/JAK/STAT3 signaling mediated by USP22, serving as an inhibitor in NSCLC [18]."
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"It remains to be determined whether miR-30e-5p can reduce NSCLC tumorigenesis by inhibiting USP22-mediated regulation of MDMX and cyclooxygenase 2.Taken together, our findings indicate that miR-30e-5p[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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