IndraLab

Statements

OTUB1 leads to the ubiquitination of FOXM1. 3 / 5
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"XREF_BIBR, XREF_BIBR However, we demonstrate here that OTUB1 suppresses the ubiquitination and degradation of FOXM1 through its deubiquitinase enzymatic activity."
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"OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance."
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"Collectively, these data suggest that OTUB1 limits the ubiquitination and degradation of FOXM1 in breast cancer and has a key role in genotoxic agent resistance."
26148240