IndraLab

Statements

Tioguanine inhibits USP2. 4 / 4
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eidos
"( C ) Noncompetitive inhibition of USP2 by 6TG ."
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eidos
"Slow-binding inhibition of USP2 by 6TG ."
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sparser
"Previous studies indicated that 6-TG could non-competitively inhibit human USP2 ( xref ) thus plays a critical role in tumor cells survival."
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eidos
"Overall , the ternary complex structure of USP2-Ub-6TG suggests the existence of an enzyme-substrate-inhibitor ( ESI ) complex and confirms the noncompetitive mechanism of USP2 inhibition by 6TG ."
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