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USP18 increases the amount of CGAS. 3 / 3
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"Western blot analysis showed that interfering cGAS suppressed the increase of cGAS protein levels caused by overexpression of USP18 ( Fig. 5 A) and attenuated the induction of STING, TBK1, IRF3 and p6[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"The above results suggested that USP18 may promote the expression of cGAS in melanoma through ubiquitination.In this study, we collected 28 cases of cancer tissues of vemurafenib-treated patients with[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Besides, we found that overexpression of USP18 again raised cGAS protein levels, and STING, TBK1, IRF3 and p65 phosphorylation levels in PR8-infected A549 cells, whereas these were reduced by interfer[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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