IndraLab

Statements


USP9X deubiquitinates CDC20. 3 / 3
| 3

reach
"In summary, the data presented here show that USP9X antagonizes Cdc20 auto-ubiquitination and degradation to limit the turnover of MCC complexes by APC/C."

reach
"We hypothesize that USP9X deubiquitinates Cdc20 directly; however, we can not rule out the possibility that USP9X loss enhances Cdc20 ubiquitination and degradation indirectly."

reach
"Interestingly, it has been shown that deubiquitinase ubiquitin‐specific peptidase 9 X‐linked (USP9X) could inhibit ubiquitination and degradation of Cdc20, thus reinforcing the SAC."