Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

PABPC1 activates PAN2. 2 / 2

| 2

➶

reach

"Because Pab1 stimulates Pan2 and interacts directly with Pan3 through its C-terminal region, an alternative interpretation could be that removal of the corresponding Pab1 domain inhibits deadenylation by preventing Pan2 action."

17766253

➶

reach

"Since Pab1 promotes Pan2 activity, one model is that this deadenylation reflects Pab1 bound to the first ~ 65 residues of the A tail, but the 3 ' most region is exposed and thereby rapidly deadenylated by Pan2."

22785621

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...