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USP27X-C87A deubiquitinates SETD3. 1 / 1
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"As seen in Fig. 2C, an enzyme-inactive mutant of USP27 (C87A) failed to abolish the ubiquitination of SETD3 protein compared with the wild-type (WT) USP27, implying that the DUB activity is required for USP27 to remove ubiquitin from SETD3."