
IndraLab
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"MK2 and MK3 phosphorylate a Beclin 1 peptide spanning S90 in vitro; MK2 and MK3 phosphorylate Beclin 1 immunoprecipitated from cells in vitro; dominant negative MK2 blocks starvation-induced Beclin 1 S90 phosphorylation and constitutively active MK2 induces Beclin 1 S90 starvation during basal conditions; and MEFs from MK2/MK3 knockout mice are deficient in starvation-induced Beclin 1 S90 phosphorylation."