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HERG-A422T activates KCNH2. 1 / 1

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"Associated with LQT2, HERG-A422T produces trafficking defective HERG K + channels (K v 11.1) that decrease the rapidly activating delayed rectifier current (I Kr), which is normally responsible for the bulk of ventricular repolarization."

25254341

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HERG-A422T activates KCNH2. 1 / 1

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