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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

HSPB8 activates ATXN3. 1 / 1

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"In fact, HSPB8 enhances the autophagy clearance of beta-amyloid, alpha-synuclein (alpha-syn), the polyQ proteins huntingtin, ataxin-3, and ARpolyQ, as well as all five DPRs from the C9orf72 mRNA, while HSPB8 downregulation has the opposite effects."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...