IndraLab

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HSPB8 activates ATXN3. 1 / 1
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"In fact, HSPB8 enhances the autophagy clearance of beta-amyloid, alpha-synuclein (alpha-syn), the polyQ proteins huntingtin, ataxin-3, and ARpolyQ, as well as all five DPRs from the C9orf72 mRNA, while HSPB8 downregulation has the opposite effects."