IndraLab

Statements


KCNG1 binds KH3. 3 / 3
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"We found that the KH2 can interact with both KH1 and KH3, and KH3 alone can activate the reporter gene expression in yeast cells (XREF_SUPPLEMENTARY)."

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"NMR CSP data obtained titrating 15 N labelled KH23 with the TNFalpha 12mer (XREF_FIG A) revealed not only that both KH2 and KH3 bind RNA using the ' classical ' nucleic acid binding grooves (XREF_FIG B), but also that KH2- and KH3 binding surfaces do not coalesce."

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"Our data indicate that an interaction between KH2 and KH3 is taking place in which the linker plays a pivotal role."