IndraLab

Statements

Gliotoxin inhibits PSMD14. 2 / 2
| 2
reach
"However, recent studies using the polyubiquitinated protein substrate Ub GST-Wbp2 (WW domain-binding protein 2, n > 30) to measure 26S proteasome-mediated protein degradation have revealed that gliotoxin and other ETPs inhibit proteasome activity in vitro and in cells by targeting the essential deubiquitinase Rpn11 [30,31] in the 19S regulatory complex of the 26S proteasome [111]."
| PMC
reach
"This assay has demonstrated that gliotoxin and other ETPs inhibit proteasome activity by targeting the essential deubiquitinase Rpn11 in the 19S regulatory complex of the 26S proteasome [111]."
| PMC