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Beta2 ICD activates SCN1A. 1 / 1

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"The beta2 ICD released by sequential BACE1 and gamma-secretase cleavage localizes to the nucleus and increases SCN1A mRNA and Na v 1.1 protein levels, suggesting that the cleaved beta2 ICD may function as a transcription regulator."

18940784

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IndraLab

Statements

Beta2 ICD activates SCN1A. 1 / 1

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