IndraLab

Statements

reach
"In summary, our results demonstrate that tetra-n-octylammonium bromide and benzethonium chloride inhibit HERG channel currents in the voltage dependent and use dependent manners."
23313619
reach
"In the present study, the potential mechanisms for HERG channel inhibition by tetra-n-octylammonium bromide and benzethonium chloride, two most potent HERG channel inhibitors found among the QACs examined, were studied using whole-cell patch clamp experiments in a CHO cell line stably expressing HERG channels."
23313619
reach
"Use dependent inhibition of HERG channels by tetra-n-octylammonium bromide and benzethonium chloride."
23313619
reach
"The study of mechanism of HERG channel inhibition by tetra-n-octylammonium bromide and benzethonium chloride can provide additional insight of structure activity relationship of HERG channel inhibition and the molecular determinants of the interaction between the compounds and HERG channel proteins."
23313619
reach
"In this study, we found that benzethonium chloride, domiphen bromide, and tetra-n-octylammonium bromide significantly inhibited hERG channel activity in both the thallium influx assay and the patch clamp experiment."
21362439
reach
"The properties of HERG channel inhibition by tetra-n-octylammonium bromide and benzethonium chloride are highly similar to verapamil and cisapride (XREF_TABLE)."
23313619
reach
"Our data indicated that tetra-n-octylammonium bromide blocks HERG channels in both open and inactivated states (XREF_FIG), whereas benzethonium chloride preferentially blocks HERG channels in the open states."
23313619
reach
"Concentration dependent inhibition of HERG channel by tetra-n-octylammonium bromide and benzethonium chloride."
23313619