IndraLab

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USP4 binds RORC. 2 / 3

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"Importantly, USP4 interacts with RORγt and deubiquitinates its K48-linked polyubiquitination, thereby stabilizing RORγt and facilitating its function."

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"Co-immunoprecipitation experiments using human CD4 + T cell lysates demonstrated that USP4 associates with RORγt."

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INDRA sources:

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IndraLab

Statements

USP4 binds RORC. 2 / 3

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